Invention Grant
- Patent Title: Modulation of synaptic maintenance
- Patent Title (中): 突触维持调制
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Application No.: US11636001Application Date: 2006-12-08
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Publication No.: US08148330B2Publication Date: 2012-04-03
- Inventor: Ben A. Barres , Beth A. Stevens
- Applicant: Ben A. Barres , Beth A. Stevens
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agency: Bozicevic, Field & Francis LLP
- Agent Elizabeth A. Alcamo
- Main IPC: A61K38/55
- IPC: A61K38/55 ; C07K17/10
Abstract:
C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including Alzheimer's disease.
Public/Granted literature
- US20070135753A1 Modulation of synaptic maintenance Public/Granted day:2007-06-14
Information query
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