Invention Grant
- Patent Title: Polymerase
- Patent Title (中): 聚合酶
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Application No.: US12830157Application Date: 2010-07-02
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Publication No.: US08148126B2Publication Date: 2012-04-03
- Inventor: Walter N. Callen , Eric J. Mathur
- Applicant: Walter N. Callen , Eric J. Mathur
- Applicant Address: US CA San Diego
- Assignee: Verenium Corporation
- Current Assignee: Verenium Corporation
- Current Assignee Address: US CA San Diego
- Agency: Verenium Corp.
- Agent Brian W. Siddons; Lynn M. Linkowski
- Main IPC: C12N9/12
- IPC: C12N9/12
Abstract:
The invention relates to thermostable polymerases that have polymerase activity temperatures in the range from 90.degree. C. up to 113.degree. C., such as those derived from Pyrolobus fumaria, and to polynucleotides encoding the polymerases In addition, methods of designing new thermostable DNA polymerases and methods of use thereof are also provided. The polymerases have increased activity and stability at increased pH and temperature.
Public/Granted literature
- US20110195479A1 POLYMERASE Public/Granted day:2011-08-11
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