Invention Grant
- Patent Title: CD95L or trail fusion proteins
- Patent Title (中): CD95L或跟踪融合蛋白
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Application No.: US12439486Application Date: 2007-08-28
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Publication No.: US08147843B2Publication Date: 2012-04-03
- Inventor: Oliver Hill , Christian Gieffers , Meinolf Thiemann
- Applicant: Oliver Hill , Christian Gieffers , Meinolf Thiemann
- Applicant Address: DE Heidelberg
- Assignee: Apogenix GmbH
- Current Assignee: Apogenix GmbH
- Current Assignee Address: DE Heidelberg
- Agency: Perkins Coie LLP
- Agent Viola T. Kung
- Priority: EP06017891 20060828
- International Application: PCT/EP2007/007517 WO 20070828
- International Announcement: WO2008/025516 WO 20080306
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K38/00 ; C07K14/525 ; C12N15/00
Abstract:
The present invention refers to fusion proteins comprising a TNF superfamily (TNFSF) cytokine or a receptor binding domain thereof fused to a trimerization domain and a nucleic acid molecule encoding the fusion protein. The fusion protein is present as a trimeric complex or as an oligomer thereof and is suitable for therapeutic, diagnostic and/or research applications.
Public/Granted literature
- US20110027218A1 TNF SUPERFAMILY FUSION PROTEINS Public/Granted day:2011-02-03
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