Invention Grant
- Patent Title: Mutant luciferase
- Patent Title (中): 突变型萤光素酶
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Application No.: US12304631Application Date: 2007-01-26
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Publication No.: US08147842B2Publication Date: 2012-04-03
- Inventor: Kosei Kawasaki , Yousuke Morita , Satoru Ohgiya , Yoshihiro Ohmiya , Yasushi Ohyama
- Applicant: Kosei Kawasaki , Yousuke Morita , Satoru Ohgiya , Yoshihiro Ohmiya , Yasushi Ohyama
- Applicant Address: JP Tokyo
- Assignee: National Institute of Advanced Industrial Science and Technology
- Current Assignee: National Institute of Advanced Industrial Science and Technology
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2006-162662 20060612
- International Application: PCT/JP2007/051279 WO 20070126
- International Announcement: WO2007/144990 WO 20071221
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C12N9/02 ; C07H21/04
Abstract:
An object of the present invention is to provide a mutant luciferase having luciferase activity with an altered emission spectrum. A specific amino acid residue(s) is substituted in a luciferase derived from Cypridina noctiluca and then the resulting mutant luciferase having luciferase activity with an emission spectrum differing from that of the wild-type luciferase is screened for.
Public/Granted literature
- US20090263880A1 MUTANT LUCIFERASE Public/Granted day:2009-10-22
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