Invention Grant
US08147840B2 Human immunodeficiency virus (HIV) immunization strategies employing conformationally-stabilized, surface-occluded peptides comprising a gp41 2F5 epitope in association with lipid
有权
使用构象稳定的表面封闭肽的人免疫缺陷病毒(HIV)免疫策略,其包含与脂质相关的gp41 2F5表位
- Patent Title: Human immunodeficiency virus (HIV) immunization strategies employing conformationally-stabilized, surface-occluded peptides comprising a gp41 2F5 epitope in association with lipid
- Patent Title (中): 使用构象稳定的表面封闭肽的人免疫缺陷病毒(HIV)免疫策略,其包含与脂质相关的gp41 2F5表位
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Application No.: US11596494Application Date: 2005-05-13
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Publication No.: US08147840B2Publication Date: 2012-04-03
- Inventor: Gilad Ofek , Peter D. Kwong , Richard Wyatt , Min Tang
- Applicant: Gilad Ofek , Peter D. Kwong , Richard Wyatt , Min Tang
- Applicant Address: US MD Bethesda
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MD Bethesda
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/US2005/016633 WO 20050513
- International Announcement: WO2005/111079 WO 20051124
- Main IPC: A61K39/21
- IPC: A61K39/21 ; A61K39/385 ; A61K9/127

Abstract:
This invention relates to novel peptide immunogens that generate an immune response in mammals against HIV gp41, to pharmaceutical compositions that comprise such immunogens, and to methods of treating Immunodeficiency disease, especially HIV infection and AIDS, that employ such pharmaceutical compositions.
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