A manufacturing apparatus of a fiber-reinforced resin strand including spreaders that spread a reinforcing fiber bundle and are provided inside a crosshead to which a molten resin material is supplied continuously from an extruding machine, twisting rollers provided at a downstream position from an exit nozzle of the crosshead and that pultrude a fiber-reinforced resin strand formed of a resin-impregnated fiber bundle from the exit nozzle while imparting twists thereto, and twist retaining rollers provided at a downstream position from the twisting rollers and that retain twists of the fiber-reinforced resin strand. The twisting rollers and the twist retaining rollers are made of metal with asperities being formed on the surface thereof. The manufacturing apparatus can achieve excellent durability and is capable of manufacturing a fiber-reinforced resin strand at a high production rate without causing slipping.