A disposable self-destruction safety syringe without fluid residua comprises a syringe tube (1), a push rod (2), a needle mount (3) and a needle (4). The push rod (2) and the needle mount (3) are mounted in the syringe tube (1). A plunger (5) slidably fitting with the inside wall of the syringe tube (1) is provided on the front end of the push rod (2). Wherein, an automatic retraction means (6) is mounted in the front end of the chamber of the push rod (2). The automatic retraction means (6) and the needle mount (3) are each provided with a snap-latch member, respectively, for connecting the needle mount (3) with the automatic retraction means (6). Each of said snap-latch member is provided with a fluid pass channel, such that the fluid remaining inside the syringe tube (1) flows, through the fluid pass channel when the snap-latch members form an interference fit and engage with each other, into the chamber of the needle mount (3) and the needle (4).