A motion guide device is provided which comprises a chain of rollers in which retainers are interposed, in which the chain of rollers is given a degree of freedom of rotation. The motion guide device comprises a track member (5) on which a roller rolling part (5a) is formed which allows rollers (7) to roll on along the roller rolling part; a moving member (6) on which a loaded roller rolling part (6a) facing the roller rolling part (5a) is formed; a plurality of rollers (7) arranged on a roller circulation path containing a loaded roller rolling path (9) formed between the roller rolling part (5a) of the track member (5) and the roller rolling part (6a) of the moving member (6); and a plurality of retainers (8) respectively interposed between rollers of the plurality of rollers (7). The plurality of retainers (8) are mutually separated, each of the retainers (8) which is divided into a first divided member (31) contacting one roller of a pair of rollers (7) with each retainer (8) sandwiched therebetween and a second divided member (32) contacting the other roller (7) of the pair of rollers, and the first divided member (31) is allowed to rotate relative to the second divided member (32).