Invention Grant
- Patent Title: Hydrazide containing taxane conjugates
- Patent Title (中): 含有紫杉烷共轭物的酰肼
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Application No.: US12918985Application Date: 2009-02-12
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Publication No.: US08133888B2Publication Date: 2012-03-13
- Inventor: Jiten Ranchhodbhai Patel , Gopalkumar Chimanlal Patel , Gaurav Sanjivkumar Sheth , Trinadha Rao Chitturi , Rajamannar Thennati
- Applicant: Jiten Ranchhodbhai Patel , Gopalkumar Chimanlal Patel , Gaurav Sanjivkumar Sheth , Trinadha Rao Chitturi , Rajamannar Thennati
- Applicant Address: IN Andheri (E), Mumbai
- Assignee: Sun Pharma Advanced Research Company Ltd.
- Current Assignee: Sun Pharma Advanced Research Company Ltd.
- Current Assignee Address: IN Andheri (E), Mumbai
- Agency: Schwegman, Lundberg & Woessner, P.A.
- Priority: IN378/MUM/2008 20080221
- International Application: PCT/IN2009/000112 WO 20090212
- International Announcement: WO2010/079499 WO 20100715
- Main IPC: A61K31/337
- IPC: A61K31/337 ; A61K31/4523 ; A61K31/5377 ; C07D305/14 ; C07D405/12 ; C07D413/12

Abstract:
The present invention relates to compounds of formula I or salts thereof, wherein, R1 is selected from the group consisting of hydrogen and R4; R2 is selected from the group consisting of hydrogen, acetyl and R4; R3 is selected from the group consisting of alkyl, —O-alkyl, —NH-alkyl, aryl and heterocyclyl; R4 represents a moiety (A) wherein, X is selected from the group consisting of a single bond, alkylene, alkenylene, alkynylene, arylene or a heterocyclylene moiety; R5 and R6 are same or different and are independently selected from hydrogen, alkyl, aryl or heterocyclyl; or R5 and R6 may form together with the nitrogen atom to which they are attached a heterocyclyl ring system.
Public/Granted literature
- US20110172226A1 NOVEL HYDRAZIDE CONTAINING TAXANE CONJUGATES Public/Granted day:2011-07-14
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