Multipath signals are processed to suppress interference utilizing a programmable interface suppression module. One or more circuits that are operable to retrieve at least a portion of stored data from a memory, wherein the stored data corresponds to signals received via a particular receiving antenna and assigned to a particular finger in a rake receiver. A plurality of weighting factor values may be computed based on one or more signals received via the particular receiving antenna. Estimated signals may be generated based on the portion of stored data and the plurality of weighting factors. Residual signals may be generated based on the portion of stored data and the estimated signals. The portion of stored data may be replaced in the memory with corresponding data generated utilizing the residual signals. A plurality of interference suppressed signals may be generated based on the plurality of residual signals.