Invention Grant
US08129396B2 2-[1H-benzimidazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and 2-[benzothiazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides as kinase inhibitors
失效
2- [1H-苯并咪唑-2（3H） - 亚基] -2-（嘧啶-2-基）乙酰胺和2- [苯并噻唑-2（3H） - 亚基] -2-（嘧啶-2-基） 激酶抑制剂
![2-[1H-benzimidazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and 2-[benzothiazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides as kinase inhibitors](/docs/US/2012-03-06/US08129396B2/abs.jpg.600x600.jpg)
- Patent Title: 2-[1H-benzimidazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and 2-[benzothiazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides as kinase inhibitors
- Patent Title (中): 2- [1H-苯并咪唑-2（3H） - 亚基] -2-（嘧啶-2-基）乙酰胺和2- [苯并噻唑-2（3H） - 亚基] -2-（嘧啶-2-基） 激酶抑制剂
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Application No.: US12567060Application Date: 2009-09-25
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Publication No.: US08129396B2Publication Date: 2012-03-06
- Inventor: Natalia Aurrecoechea , Paul P. Beroza , Komath V. Damodaran , Karen Y. Pontius , Louise Robinson , Reyna J. Simon , Truong Vu , Kevin T. Weber
- Applicant: Natalia Aurrecoechea , Paul P. Beroza , Komath V. Damodaran , Karen Y. Pontius , Louise Robinson , Reyna J. Simon , Truong Vu , Kevin T. Weber
- Applicant Address: US CA Palo Alto
- Assignee: Telik, Inc.
- Current Assignee: Telik, Inc.
- Current Assignee Address: US CA Palo Alto
- Agency: Foley & Lardner LLP
- Main IPC: C07D239/42
- IPC: C07D239/42 ; C07D401/04 ; C07D239/02
![2-[1H-benzimidazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and 2-[benzothiazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides as kinase inhibitors](/abs-image/US/2012/03/06/US08129396B2/abs.jpg.150x150.jpg)
Abstract:
2-[1H-benzimidazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and 2-[benzothiazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and their salts are kinase inhibitors, useful in the treatment of cancer.
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