Invention Grant
US08129387B2 Substituted 5,6-dihydroimidazo[1,5-F]pteridines useful as protein kinase inhibitors
失效
用作蛋白激酶抑制剂的取代的5,6-二氢咪唑并[1,5-F]蝶啶
- Patent Title: Substituted 5,6-dihydroimidazo[1,5-F]pteridines useful as protein kinase inhibitors
- Patent Title (中): 用作蛋白激酶抑制剂的取代的5,6-二氢咪唑并[1,5-F]蝶啶
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Application No.: US12448258Application Date: 2007-12-14
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Publication No.: US08129387B2Publication Date: 2012-03-06
- Inventor: Jean-Damien Charrier , Ronald Knegtel , David Kay
- Applicant: Jean-Damien Charrier , Ronald Knegtel , David Kay
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agency: Honigman Miller Schwartz and Cohn LLP
- Agent Jonathan P. O'Brien; Andrew N. Weber
- International Application: PCT/US2007/025688 WO 20071214
- International Announcement: WO2008/076392 WO 20080626
- Main IPC: A61K31/495
- IPC: A61K31/495
![Substituted 5,6-dihydroimidazo[1,5-F]pteridines useful as protein kinase inhibitors](/abs-image/US/2012/03/06/US08129387B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to substituted 5,6-dihydroimidazo[1,5-f]pteridines of formula I: which are useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the invention.
Public/Granted literature
- US20100099686A1 COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS Public/Granted day:2010-04-22
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