Invention Grant
- Patent Title: Treatment of neurological disorders by dsRNA administration
- Patent Title (中): 通过dsRNA给药治疗神经系统疾病
-
Application No.: US11779098Application Date: 2007-07-17
-
Publication No.: US08129354B2Publication Date: 2012-03-06
- Inventor: Gabriele Dorn , Pamposh Ganju , Jonathan Hall , Maria Wanda Hemmings , William Leonard Wishart
- Applicant: Gabriele Dorn , Pamposh Ganju , Jonathan Hall , Maria Wanda Hemmings , William Leonard Wishart
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Frank Wu
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C07H21/04

Abstract:
The present invention relates to methods to treat neurological disorders comprising intrathecal injection of an effective amount of a double-stranded (ds) RNA into a subject in need, wherein the dsRNA inhibits the expression of a target gene and to pharmaceutical compositions useful for such treatment.
Public/Granted literature
- US20080153768A1 TREATMENT OF NEUROLOGICAL DISORDERS BY DSRNA ADMINISTRATION Public/Granted day:2008-06-26
Information query
IPC分类: