Invention Grant
- Patent Title: Antibodies against PDGFRa
- Patent Title (中): 抗PDGFRa抗体
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Application No.: US11917890Application Date: 2006-06-19
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Publication No.: US08128929B2Publication Date: 2012-03-06
- Inventor: Nick Loizos , Jim Huber
- Applicant: Nick Loizos , Jim Huber
- Applicant Address: US NY New York
- Assignee: ImClone LLC
- Current Assignee: ImClone LLC
- Current Assignee Address: US NY New York
- Agent Nicole S. Woods
- International Application: PCT/US2006/023856 WO 20060619
- International Announcement: WO2008/138729 WO 20061228
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K31/704 ; A61K31/337
Abstract:
The invention provides antibodies that bind to human PDGFRα and neutralize activation of the receptor. The invention further provides methods for neutralizing activation of PDGFRα and methods of treating a mammal with a neoplastic disease using the antibodies alone or in combination with other agents.
Public/Granted literature
- US20090110678A1 RECEPTOR ANTAGONISTS FOR TREATMENT OF METASTATIC BONE CANCER Public/Granted day:2009-04-30
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