Invention Grant
- Patent Title: Manufacture of active highly phosphorylated human lysosomal sulfatase enzymes and uses thereof
- Patent Title (中): 活性高度磷酸化人溶酶体硫酸酯酶的制备及其用途
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Application No.: US12355453Application Date: 2009-01-16
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Publication No.: US08128925B2Publication Date: 2012-03-06
- Inventor: Michel Claude Vellard , Vish Koppaka , Melita Dvorak-Ewell , Erno Pungor , Charles Hague
- Applicant: Michel Claude Vellard , Vish Koppaka , Melita Dvorak-Ewell , Erno Pungor , Charles Hague
- Applicant Address: US CA Novato
- Assignee: Biomarin Pharmaceutical Inc.
- Current Assignee: Biomarin Pharmaceutical Inc.
- Current Assignee Address: US CA Novato
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: A61K38/46
- IPC: A61K38/46 ; C12N9/14
Abstract:
This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
Public/Granted literature
- US20090186011A1 Manufacture of Active Highly Phosphorylated Human Lysosomal Sulfatase Enzymes and Uses Thereof Public/Granted day:2009-07-23
Information query
IPC分类:
