Embodiments include systems and methods of detecting fraud. In particular, one embodiment includes a system and method of detecting fraud in mortgage applications. For example, one embodiment includes a computerized method of detecting fraud that includes receiving mortgage data associated with an applicant and at least one entity related to processing of the mortgage data, determining a first score for the mortgage data based at least partly on a first model that is based on data from a plurality of historical mortgage transactions associated with the entity, and generating data indicative of fraud based at least partly on the first score. Other embodiments include systems and method of generating models for use in fraud detection systems.