Method, mobile station, base station and computer program product for transmission power control in a wireless communication comprising the adjustment of the retransmission power for at least a part of an unsuccessfully received data block at a receiver according to the received information indicative of the channel qualities after an unsuccessful reception of the transmitted data block and prior to a retransmission of at least a part of the unsuccessfully transmitted data block and according to a required channel quality necessary for reaching a target BLEP (Block-Error Probability).