A system, method and program product for securely saving a program context to a shared memory is presented. A secured program running on an special purpose processor core running in isolation mode is interrupted. The isolated special purpose processor core is included in a heterogeneous processing environment, that includes purpose processors and general purpose processor cores that each access a shared memory. In isolation mode, the special purpose processor core's local memory is inaccessible from the other heterogeneous processors. The secured program's context is securely saved to the shared memory using a random persistent security data. The lines of code stored in the isolated special purpose processor core's local memory are read along with data values, such as register settings, set by the secured program. The lines of code and data values are encrypted using the persistent security data, and the encrypted code lines and data values are stored in the shared memory.