Invention Grant
- Patent Title: Method for deblocking of labeled oligonucleotides
- Patent Title (中): 标记寡核苷酸解封的方法
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Application No.: US10365644Application Date: 2003-02-13
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Publication No.: US08093372B2Publication Date: 2012-01-10
- Inventor: Gulilat Gebeyehu , Richard M Pires
- Applicant: Gulilat Gebeyehu , Richard M Pires
- Applicant Address: US CA Carlsbad
- Assignee: Life Technologies Corporation
- Current Assignee: Life Technologies Corporation
- Current Assignee Address: US CA Carlsbad
- Main IPC: C07H21/00
- IPC: C07H21/00
Abstract:
The invention relates to a process for deblocking substantially a blocked, detectably labeled oligonucleotide by contacting the blocked detectably labeled oligonucleotide with an effective amount of a nucleophilic amino compound under conditions that result in substantial deblocking of the oligonucleotide, thereby giving the substantially deblocked oligonucleotide.
Public/Granted literature
- US20030120063A1 Method for deblocking of labeled oligonucleotides Public/Granted day:2003-06-26
Information query
