Invention Grant
US07989663B2 Compounds and methods of use thereof for assaying lysophospholipase D activity
有权
用于测定溶血磷脂酶D活性的化合物及其使用方法
- Patent Title: Compounds and methods of use thereof for assaying lysophospholipase D activity
- Patent Title (中): 用于测定溶血磷脂酶D活性的化合物及其使用方法
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Application No.: US12290293Application Date: 2008-10-28
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Publication No.: US07989663B2Publication Date: 2011-08-02
- Inventor: Colin Ferguson , Glenn Prestwich
- Applicant: Colin Ferguson , Glenn Prestwich
- Applicant Address: US UT Salt Lake City
- Assignee: Echelon Biosciences Incorporated
- Current Assignee: Echelon Biosciences Incorporated
- Current Assignee Address: US UT Salt Lake City
- Agency: The McCallum Law Firm, P.C.
- Agent Jennifer M. McCallum, Esq.
- Main IPC: C07F9/02
- IPC: C07F9/02
Abstract:
Fluorogenic lysophosphatidic acid derivatives which can be used as substrates in a continuous, fluorogenic assay that can be performed in microtiter plates. The assays permit measuring LysoPLD activity levels in normal events such as pregnancy or disease states such as cancer. In addition, the present invention can be adopted to high throughout screening (HTS) for identification of potential inhibitors of lysoPLD activity.
Public/Granted literature
- US20090068697A1 Compounds and methods of use thereof for assaying lysophospholipase D activity Public/Granted day:2009-03-12
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