Invention Grant
US07989615B2 Separation of different isoforms of plasmid DNA using ultrafiltration
失效
使用超滤分离质粒DNA的不同同种型
- Patent Title: Separation of different isoforms of plasmid DNA using ultrafiltration
- Patent Title (中): 使用超滤分离质粒DNA的不同同种型
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Application No.: US12217777Application Date: 2008-07-09
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Publication No.: US07989615B2Publication Date: 2011-08-02
- Inventor: Andrew Lawrence Zydney , David Robert Latulippe
- Applicant: Andrew Lawrence Zydney , David Robert Latulippe
- Applicant Address: US PA University Park
- Assignee: The Penn State Research Foundation
- Current Assignee: The Penn State Research Foundation
- Current Assignee Address: US PA University Park
- Agent Barbara E. Johnson, Esq.
- Main IPC: C07H21/04
- IPC: C07H21/04
Abstract:
The invention is a method for isolating a desired plasmid DNA isoform, typically a supercoiled isoform, which includes the steps of obtaining a quantity of bioreactor produced plasmid DNA in liquid form for purification, and passing the plasmid DNA through an ultrafiltration membrane at a selected filtrate flux.
Public/Granted literature
- US20090018322A1 Separation of different isoforms of plasmid DNA using ultrafiltration Public/Granted day:2009-01-15
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