Invention Grant
- Patent Title: Expression control sequence
- Patent Title (中): 表达控制序列
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Application No.: US11002141Application Date: 2004-12-03
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Publication No.: US07989611B2Publication Date: 2011-08-02
- Inventor: Sergei Vladimirovich Mashko , Danila Vadimovich Zimenkov
- Applicant: Sergei Vladimirovich Mashko , Danila Vadimovich Zimenkov
- Applicant Address: JP Tokyo
- Assignee: Ajinomoto Co., Inc.
- Current Assignee: Ajinomoto Co., Inc.
- Current Assignee Address: JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: RU2001104817 20010222
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02

Abstract:
An expression control sequence which controls expression of a target gene linked downstream of the expression control sequence depending on an intracellular concentration of an amino acid, wherein in a bacterial cell which harbors a DNA construct comprising the expression control sequence, a promoter linked upstream of the expression control sequence and the target gene linked downstream of the expression control sequence, frequency of termination in the expression control sequence, of transcription starting from the promoter is lowered by increase of an intracellular concentration of an amino acid, whereby expression of the target gene increases.
Public/Granted literature
- US20050266525A1 Expression control sequence Public/Granted day:2005-12-01
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