Invention Grant
- Patent Title: Inhibitors of IMPDH enzyme
- Patent Title (中): IMPDH酶抑制剂
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Application No.: US10671967Application Date: 2003-09-25
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Publication No.: US07989498B2Publication Date: 2011-08-02
- Inventor: Jeffrey O Saunders , Daniel Elbaum , Perry M Novak , Douglas Naegele , Randy S Bethiel , Steven M Ronkin , Michael C Badia , Catharine Frank , Dean P Stamos , William Walters , David Pearlman
- Applicant: Jeffrey O Saunders , Daniel Elbaum , Perry M Novak , Douglas Naegele , Randy S Bethiel , Steven M Ronkin , Michael C Badia , Catharine Frank , Dean P Stamos , William Walters , David Pearlman
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agency: Ropes & Gray LLP
- Agent James F. Haley, Jr.
- Main IPC: A61K31/165
- IPC: A61K31/165 ; A61K31/16
Abstract:
The present invention relates to compounds which inhibit IMPDH. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well suited for inhibiting IMPDH enzyme activity and consequently, may be advantageously used as therapeutic agents for IMPDH mediated processes. This invention also relates to methods for inhibiting the activity of IMPDH using the compounds of this invention and related compounds.
Public/Granted literature
- US20040087650A1 Inhibitors of IMPDH enzyme Public/Granted day:2004-05-06
Information query
