Invention Grant
US07989492B2 Epigallocatechin dimers or trimers having lipase inhibitory activity and/or antioxidant activity
有权
具有脂肪酶抑制活性和/或抗氧化活性的表没食子儿茶素二聚体或三聚体
- Patent Title: Epigallocatechin dimers or trimers having lipase inhibitory activity and/or antioxidant activity
- Patent Title (中): 具有脂肪酶抑制活性和/或抗氧化活性的表没食子儿茶素二聚体或三聚体
-
Application No.: US11597291Application Date: 2005-05-26
-
Publication No.: US07989492B2Publication Date: 2011-08-02
- Inventor: Masaaki Nakai , Yuko Fukui , Sumio Asami
- Applicant: Masaaki Nakai , Yuko Fukui , Sumio Asami
- Applicant Address: JP Osaka-shi, Osaka
- Assignee: Suntory Holdings Limited
- Current Assignee: Suntory Holdings Limited
- Current Assignee Address: JP Osaka-shi, Osaka
- Agency: Drinker Biddle & Reath LLP
- Priority: JP2004-158463 20040527
- International Application: PCT/JP2005/009666 WO 20050526
- International Announcement: WO2005/116005 WO 20051208
- Main IPC: A61K31/353
- IPC: A61K31/353

Abstract:
An object of the present invention is to provide a lipase activity inhibitor that shows high inhibitory activity against pancreatic lipase to suppress the absorption of meal-derived fat and/or which contributes to suppressing and preventing obesity, as well as a food or beverage that has such lipase activity inhibitor incorporated therein. Another object of the invention is to provide a lipase inhibitor of tea origin that suits most consumers' taste and which will not impair the flavor of the food or beverage when incorporated therein. Still another object of the invention is to provide a process for producing said lipase inhibitors. Further object of the invention is to provide antioxidants. To attain these objects, epigallocatechin dimers (oolong homobisflavans) or trimers are incorporated in foods or beverages. As a result, the absorption of meal-derived fat can be suppressed and, in addition, antioxidation effect is obtained. The compounds of the invention can be produced by reacting epigallocatechin gallate with formaldehyde in the presence of an acid.
Public/Granted literature
- US20080275258A1 Epigallocatechin Dimers or Trimers Having Lipase Inhibitory Activity and/or Antioxidant Activity Public/Granted day:2008-11-06
Information query
IPC分类: