Invention Grant
US07989486B2 Use of diindolylmethane-related indoles for the treatment and prevention of respiratory syncytial virus associated conditions
有权
二吲哚基甲烷相关吲哚用于治疗和预防呼吸道合胞病毒相关病症的使用
- Patent Title: Use of diindolylmethane-related indoles for the treatment and prevention of respiratory syncytial virus associated conditions
- Patent Title (中): 二吲哚基甲烷相关吲哚用于治疗和预防呼吸道合胞病毒相关病症的使用
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Application No.: US11322803Application Date: 2005-12-30
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Publication No.: US07989486B2Publication Date: 2011-08-02
- Inventor: Michael A. Zeligs
- Applicant: Michael A. Zeligs
- Applicant Address: US CO Boulder
- Assignee: Bioresponse, L.L.C.
- Current Assignee: Bioresponse, L.L.C.
- Current Assignee Address: US CO Boulder
- Agent Jones Day
- Main IPC: A61K31/405
- IPC: A61K31/405 ; A61K38/00 ; A61K31/69 ; A61K31/59 ; A61K31/33 ; A61K31/05
Abstract:
The present invention includes compositions and methods for the treatment and prevention of conditions associated with Respiratory Syncytial Virus (RSV) infection. RSV-associated conditions include acute infections in mammals, typically bronchiolitis and pneumonia, and post-infectious chronic respiratory conditions. In particular, the present invention describes new therapeutic and preventative uses for 3,3′-diindolylmethane (DIM), or a DIM-related indole, alone or in combination with an inhibitor of a membrane bound Epidermal Growth Factor Receptor (EGFR) inhibitors, to treat conditions associated with exposure to RSV.
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