Invention Grant
- Patent Title: 4-amino 5-cyanopyrimidine derivatives
- Patent Title (中): 4-氨基-5-氰基嘧啶衍生物
-
Application No.: US12923451Application Date: 2010-09-22
-
Publication No.: US07989446B2Publication Date: 2011-08-02
- Inventor: Masaya Kato , Norifumi Sato , Minoru Okada , Tetsuyuki Uno , Nobuaki Ito , Yasuhiro Takeji , Hisashi Shinohara , Masahiro Fuwa
- Applicant: Masaya Kato , Norifumi Sato , Minoru Okada , Tetsuyuki Uno , Nobuaki Ito , Yasuhiro Takeji , Hisashi Shinohara , Masahiro Fuwa
- Applicant Address: JP Tokyo
- Assignee: Otsuka Pharmaceutical Co., Ltd.
- Current Assignee: Otsuka Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Priority: JP2004-135999 20040430
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D401/14 ; A61K31/506
Abstract:
The present invention provides 4-amino-5-cyanopyrimidine derivatives of the formula: wherein R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof, having a safe and potent adenosine A2a receptor agonistic activity; and also provides an adenosine A2a receptor agonist, an intraocular pressure reducing agent, or a medicine for treating glaucoma, etc., which comprises the compound as an active ingredient.
Public/Granted literature
- US20110009620A1 4-Amino-5-cyanopyrimidine derivatives Public/Granted day:2011-01-13
Information query
