Invention Grant
US07989188B2 Conjugates for cancer therapy and diagnosis 有权
用于癌症治疗和诊断的共轭物

Conjugates for cancer therapy and diagnosis
Abstract:
The present invention relates to conjugates of a drug and an amino acid or an amino acid derivative or analog, pharmaceutical compositions that include the conjugates and methods of use thereof. In particular, the present invention relates to conjugates of anti-proliferative drugs and asparagine and glutamine and analogs thereof as compositions for treatment of cancer, and conjugates of imaging agent carriers and amino acids for the diagnosis of tumors and metastases.
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