Invention Grant
- Patent Title: LXR ligand testing method
- Patent Title (中): LXR配体检测方法
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Application No.: US11921967Application Date: 2006-06-26
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Publication No.: US07989179B2Publication Date: 2011-08-02
- Inventor: Naoki Terasaka , Shoko Honzumi , Ira Glenn Schulman , Brandee Lynn Wagner , Patricia J. Willy
- Applicant: Naoki Terasaka , Shoko Honzumi , Ira Glenn Schulman , Brandee Lynn Wagner , Patricia J. Willy
- Applicant Address: JP Tokyo
- Assignee: Daiichi Sankyo Company, Limited
- Current Assignee: Daiichi Sankyo Company, Limited
- Current Assignee Address: JP Tokyo
- Agency: Holtz Holtz Goodman & Chick PC
- International Application: PCT/US2006/024945 WO 20060626
- International Announcement: WO2007/002654 WO 20070104
- Main IPC: C12Q1/60
- IPC: C12Q1/60
Abstract:
A method of easily measuring whether or not an LXR ligand has the function of effecting, e.g., increasing, plasma triglyceride concentration and/or LDL cholesterol concentration in a mammal by using the binding activity between LXR and a coactivator, and a method of identifying LXR ligands that do not have the function of effecting, e.g., increasing, plasma triglyceride concentration and/or LDL cholesterol concentration by using the binding activity between LXR and a coactivator.
Public/Granted literature
- US20090098570A1 Lxr ligand testing method Public/Granted day:2009-04-16
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