Invention Grant
US07988964B2 NOGO-a neutralising immunoglobulin for treatment of neurological diseases
有权
NOGO - 一种用于治疗神经系统疾病的中和免疫球蛋白
- Patent Title: NOGO-a neutralising immunoglobulin for treatment of neurological diseases
- Patent Title (中): NOGO - 一种用于治疗神经系统疾病的中和免疫球蛋白
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Application No.: US10583877Application Date: 2004-12-20
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Publication No.: US07988964B2Publication Date: 2011-08-02
- Inventor: Jonathan Henry Ellis , Alexandre Eon-Duval , Robert Ian Grundy , Farhana Hussain , Ruth McAdam , Christopher Plumpton , Rabinder Kumar Prinjha , Paul Alexander Wilson
- Applicant: Jonathan Henry Ellis , Alexandre Eon-Duval , Robert Ian Grundy , Farhana Hussain , Ruth McAdam , Christopher Plumpton , Rabinder Kumar Prinjha , Paul Alexander Wilson
- Applicant Address: GB
- Assignee: Glaxo Group Limited
- Current Assignee: Glaxo Group Limited
- Current Assignee Address: GB
- Agent Jonathan M. Dermott; William T. Han
- Priority: GB0329684.5 20031222; GB0329711.6 20031222
- International Application: PCT/GB2004/005325 WO 20041220
- International Announcement: WO2005/061544 WO 20050707
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; A61K38/00 ; C12P21/08 ; C07K16/00
Abstract:
The present invention provides immunoglobulins, particularly antibodies that bind to NOGO and neutralise the activity thereof, polynucleotides encoding such antibodies, pharmaceutical formulations containing said antibodies and to the use of such antibodies in the treatment and/or prophylaxis of neurological diseases.
Public/Granted literature
- US20070065430A1 Nogo-a neutralising immunoglobulins for treatment of neurological diseases Public/Granted day:2007-03-22
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