Aspects of a method and system for simultaneous signal transmission on multiple selected frequencies may include generating from a single baseband signal, a plurality of radio frequency transmission signals each at a different radio frequency, wherein the single baseband signal comprises an in-phase signal component and/or a quadrature signal component. The single baseband signal, to generate said plurality of radio frequency transmission signals, may be modulated in a single radio frequency transmission chain, the radio frequency transmission chain comprising intermediate frequency modulation and radio frequency modulation. The plurality of radio frequency transmission signals may be a radio frequency signal and a corresponding image frequency signal, based on the intermediate frequency modulation and the radio frequency modulation. The signals resulting from the intermediate frequency modulation and the radio frequency modulation may be filtered to preserve the radio frequency signal and the corresponding image frequency signal.