Invention Grant
- Patent Title: Modulators of ATP-Binding Cassette transporters
- Patent Title (中): ATP结合盒转运蛋白的调节剂
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Application No.: US10936448Application Date: 2004-09-07
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Publication No.: US07973169B2Publication Date: 2011-07-05
- Inventor: Sara S. Hadida Ruah , Mark T. Miller , Ashvani K. Singh , Thomas Cleveland , Lewis R. Makings , Matthew Hamilton , Peter D. J. Grootenhuis
- Applicant: Sara S. Hadida Ruah , Mark T. Miller , Ashvani K. Singh , Thomas Cleveland , Lewis R. Makings , Matthew Hamilton , Peter D. J. Grootenhuis
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agent Michael J. DiVerdi
- Main IPC: C07D277/20
- IPC: C07D277/20 ; A61K31/427
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including CF Transmembrane Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Public/Granted literature
- US20050176789A1 Modulators of ATP-Binding Cassette transporters Public/Granted day:2005-08-11
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