Invention Grant
US07973128B2 Immunogenic polypeptide composed of tumor antigen-derived optimized cryptic peptides, and uses thereof
有权
由肿瘤抗原衍生的优化的神经肽组成的免疫原性多肽及其用途
- Patent Title: Immunogenic polypeptide composed of tumor antigen-derived optimized cryptic peptides, and uses thereof
- Patent Title (中): 由肿瘤抗原衍生的优化的神经肽组成的免疫原性多肽及其用途
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Application No.: US12158736Application Date: 2005-12-23
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Publication No.: US07973128B2Publication Date: 2011-07-05
- Inventor: Kostantinos Kosmatopoulos , Sébastien Cornet
- Applicant: Kostantinos Kosmatopoulos , Sébastien Cornet
- Applicant Address: FR Evry Cedex
- Assignee: Vaxon Biotech
- Current Assignee: Vaxon Biotech
- Current Assignee Address: FR Evry Cedex
- Agency: Alston & Bird LLP
- International Application: PCT/EP2005/014212 WO 20051223
- International Announcement: WO2007/073768 WO 20070705
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K14/00 ; A61P35/00 ; C07H21/02 ; C07H21/04 ; C12N15/00 ; C12N5/00 ; C12N5/07
Abstract:
The present invention pertains to the field of anti-cancer vaccines. More particularly, the invention concerns an optimized polypeptide, which comprises three cryptic tumor peptides with enhanced immunogenicity and comprises the amino acids sequence YLQVNSLQTVYLEYRQVPVYLEEITGYL (SEQ ID NO. 2), for use in an anti-cancer vaccine. Nucleic acids encoding such a polypeptide, as well as complexes and dendritic cells engineered with this polypeptide or a nucleic acid encoding it, are also part of the invention.
Public/Granted literature
- US20090130133A1 IMMUNOGENIC POLYPEPTIDE COMPOSED OF TUMOR ANTIGEN-DERIVED OPTIMIZED CRYPTIC PEPTIDES, AND USES THEREOF Public/Granted day:2009-05-21
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