Invention Grant
- Patent Title: Thalidomide analogs
- Patent Title (中): 沙利度胺类似物
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Application No.: US10572485Application Date: 2004-09-17
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Publication No.: US07973057B2Publication Date: 2011-07-05
- Inventor: Nigel H. Greig , Harold Holloway , Arnold Brossi , Xiaoxiang Zhu , Tony Giordano , Qian-sheng Yu , William D. Figg
- Applicant: Nigel H. Greig , Harold Holloway , Arnold Brossi , Xiaoxiang Zhu , Tony Giordano , Qian-sheng Yu , William D. Figg
- Applicant Address: US DC Washington US OH Cincinnati
- Assignee: The United States of America as represented by the Department of Health and Human Services,P2D Inc.
- Current Assignee: The United States of America as represented by the Department of Health and Human Services,P2D Inc.
- Current Assignee Address: US DC Washington US OH Cincinnati
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US2004/030506 WO 20040917
- International Announcement: WO2005/028436 WO 20050331
- Main IPC: A01N43/40
- IPC: A01N43/40 ; A61K31/445
Abstract:
Thalidomide analogs that modulate tumor necrosis factor alpha (TNF-α) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs.
Public/Granted literature
- US20060211728A1 Thalidomide analogs Public/Granted day:2006-09-21
Information query
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