Invention Grant
US07973016B2 Methods of treating, reducing, or preventing autoimmune conditions
失效
治疗，减少或预防自身免疫病症的方法
- Patent Title: Methods of treating, reducing, or preventing autoimmune conditions
- Patent Title (中): 治疗，减少或预防自身免疫病症的方法
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Application No.: US10586401Application Date: 2005-01-24
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Publication No.: US07973016B2Publication Date: 2011-07-05
- Inventor: Diane Mathis , Christophe O. Benoist , Hsin-Jung Wu
- Applicant: Diane Mathis , Christophe O. Benoist , Hsin-Jung Wu
- Applicant Address: US MA Boston
- Assignee: Joslin Diebetes Center
- Current Assignee: Joslin Diebetes Center
- Current Assignee Address: US MA Boston
- Agency: Clark & Elbing LLP
- International Application: PCT/US2005/002097 WO 20050124
- International Announcement: WO2005/072290 WO 20050811
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C07H21/02 ; C07H21/04
Abstract:
The present invention relates to methods and kits for treating, reducing, or preventing autoimmune conditions such as rheumatoid arthritis by administering to a mammal in need thereof an agent that modulates the expression level or biological activity of Toll-like receptor-9 (TLR-9). Also disclosed are screening methods that make use of TLR-9 for the identification of novel therapeutics for autoimmune conditions.
Public/Granted literature
- US20080020991A1 Methods of Treating, Reducing, or Preventing Autoimmune Conditions Public/Granted day:2008-01-24
Information query
IPC分类:
