Invention Grant
- Patent Title: Liver specific chimeric regulatory sequence and use thereof
- Patent Title (中): 肝特异性嵌合调节序列及其用途
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Application No.: US11600796Application Date: 2006-11-17
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Publication No.: US07972851B2Publication Date: 2011-07-05
- Inventor: Mei-Chih Wang , Chin-Yu Lin , Hui-Ti Lin
- Applicant: Mei-Chih Wang , Chin-Yu Lin , Hui-Ti Lin
- Applicant Address: TW Hsinchu
- Assignee: Industrial Technology Research Institute
- Current Assignee: Industrial Technology Research Institute
- Current Assignee Address: TW Hsinchu
- Agency: Bacon & Thomas, PLLC
- Priority: TW93129594A 20040930
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/0735 ; C12N5/10 ; C12N5/22 ; C12N15/00 ; C07H21/04

Abstract:
The present invention relates to a chimeric regulatory sequence with liver cell specificity. The chimeric regulatory sequence includes a proximal regulatory sequence and a distal enhancer 5′ flanking region of human α-fetoprotein (AFP) gene. The chimeric regulatory sequence is useful in purified specific lineages, such as liver cells, from other cell lineages.
Public/Granted literature
- US20070072172A1 Liver specific chimeric regulatory sequence and use thereof Public/Granted day:2007-03-29
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