Invention Grant
- Patent Title: Preparation of platinum (II) complexes
- Patent Title (中): 铂(II)配合物的制备
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Application No.: US12162745Application Date: 2007-01-30
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Publication No.: US07956208B2Publication Date: 2011-06-07
- Inventor: Jan Gysbert Hermanus Du Preez
- Applicant: Jan Gysbert Hermanus Du Preez
- Applicant Address: ZA Port Elizabeth
- Assignee: Platco Technologies (Proprietary) Limited
- Current Assignee: Platco Technologies (Proprietary) Limited
- Current Assignee Address: ZA Port Elizabeth
- Agency: Morrison & Foerster LLP
- International Application: PCT/IB2007/000213 WO 20070130
- International Announcement: WO2007/085957 WO 20070802
- Main IPC: C07F15/00
- IPC: C07F15/00

Abstract:
This invention relates a method for the preparation of platinum(II) oxalato complexes from their dihalogenoplatinum(II) precursors having either neutral monodentate or bidentate non-leaving co-ligands. Of particular interest is oxaliplatin. The method includes the step of reacting a halogenoplatinum(II) complex containing a neutral monodentate or bidentate ligand with an oxalate in a non-aqueous solvent or a mixed solvent system. The mixed solvent system is solvent mixture containing a non-aqueous solvent and water. According to the present invention, the non-aqueous solvent is an alcohol.
Public/Granted literature
- US20090281319A1 PREPARATION OF PLATINUM (II) COMPLEXES Public/Granted day:2009-11-12
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