Invention Grant
- Patent Title: 3-arylamino pyridine derivatives
- Patent Title (中): 3-芳基氨基吡啶衍生物
-
Application No.: US11665651Application Date: 2005-10-19
-
Publication No.: US07956191B2Publication Date: 2011-06-07
- Inventor: Ulrich Abel , Holger Deppe , Achim Feurer , Ulrich Grädler , Kerstin Otte , Renate Sekul , Meinolf Thiemann , Andreas Goutopoulos , Matthias Schwarz , Xuliang Jiang
- Applicant: Ulrich Abel , Holger Deppe , Achim Feurer , Ulrich Grädler , Kerstin Otte , Renate Sekul , Meinolf Thiemann , Andreas Goutopoulos , Matthias Schwarz , Xuliang Jiang
- Applicant Address: CH Coinsins, Vaud
- Assignee: Merck Serono SA
- Current Assignee: Merck Serono SA
- Current Assignee Address: CH Coinsins, Vaud
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- Priority: EP04024967 20041020
- International Application: PCT/EP2005/011257 WO 20051019
- International Announcement: WO2006/045514 WO 20060504
- Main IPC: C07D213/72
- IPC: C07D213/72 ; C07D213/46
Abstract:
The invention provides novel, substituted 3-arylamino pyridine compounds (I) pharmaceutically acceptable salts, solvates and prodrug compounds thereof, wherein W, R1, R2, R9, R10, R11, R12, R13, R14 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer, restenosis and inflammation. Also disclosed is the use of such compounds in the treatment of hyperproliferative diseases in mammals, especially humans, and pharmaceutical compositions containing such compounds.
Public/Granted literature
- US20090093462A1 3-Arylamino pyridine derivatives Public/Granted day:2009-04-09
Information query
