Invention Grant
- Patent Title: Protein stabilization formulations
- Patent Title (中): 蛋白质稳定配方
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Application No.: US11950127Application Date: 2007-12-04
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Publication No.: US07956028B2Publication Date: 2011-06-07
- Inventor: Venkata R. Garigapati , Dongling Su , Rehan Khanzada , Steven J. Sawamura
- Applicant: Venkata R. Garigapati , Dongling Su , Rehan Khanzada , Steven J. Sawamura
- Applicant Address: US MA Raynham
- Assignee: Johnson & Johnson Regenerative Therapeutics, LLC
- Current Assignee: Johnson & Johnson Regenerative Therapeutics, LLC
- Current Assignee Address: US MA Raynham
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/16 ; A61K38/17 ; A61K38/18 ; C07K14/00 ; C07K14/435 ; C07K14/46 ; C07K14/47 ; C07K14/475 ; C07K14/51
Abstract:
The present invention is directed to stabilizing Bone Morphogenetic Protein in various lyophilized formulations and compositions. The present invention comprises formulations primarily including trehalose as an excipient for lyophilized compositions and their subsequent storage and reconstitution, and can also optionally include other excipients, including buffers and surfactants.
Public/Granted literature
- US20080147077A1 Protein stabilization formulations Public/Granted day:2008-06-19
Information query
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