Invention Grant
- Patent Title: Vaccine protection assay
- Patent Title (中): 疫苗保护试验
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Application No.: US11469204Application Date: 2006-08-31
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Publication No.: US07955817B2Publication Date: 2011-06-07
- Inventor: Isabel De Vleeschauwer , Nathalie Durant , Jan Poolman , Vincent Weynants
- Applicant: Isabel De Vleeschauwer , Nathalie Durant , Jan Poolman , Vincent Weynants
- Applicant Address: BE Rixensart
- Assignee: GlaxoSmithKline Biologicals S.A.
- Current Assignee: GlaxoSmithKline Biologicals S.A.
- Current Assignee Address: BE Rixensart
- Agent Virginia G. Campen
- Priority: EPPCT/EP05/09566 20050905
- Main IPC: C12Q1/18
- IPC: C12Q1/18

Abstract:
The present invention relates to the field of Serum Bactericidal Activity (SBA) assays for Gram negative bacteria, in particular N. meningitidis. The SBA assay is the most important method for measuring functional activity of serum antibodies against meningococcus. In order to determine whether a subject or a population is seropositive against invasive meningococcus the SBA test should ideally be both sensitive and specific. The inventors have found the standard N. meningitidis serotype A and W SBAs can be significantly improved in this regard.
Public/Granted literature
- US20080064057A1 Vaccine Protection Assay Public/Granted day:2008-03-13
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