Invention Grant
US07955815B2 Two-photon fluorescent probes for acidic vesicles in live cells and tissue and method of imaging acidic vesicles in live cells and tissue using the same
有权
用于活细胞和组织中的酸性囊泡的双光子荧光探针和使用其在活细胞和组织中成像酸性囊泡的方法
- Patent Title: Two-photon fluorescent probes for acidic vesicles in live cells and tissue and method of imaging acidic vesicles in live cells and tissue using the same
- Patent Title (中): 用于活细胞和组织中的酸性囊泡的双光子荧光探针和使用其在活细胞和组织中成像酸性囊泡的方法
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Application No.: US12288101Application Date: 2008-10-15
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Publication No.: US07955815B2Publication Date: 2011-06-07
- Inventor: Bong-Rae Cho
- Applicant: Bong-Rae Cho
- Applicant Address: KR Seoul
- Assignee: Korea University Industrial & Academic Collaboration Foundation
- Current Assignee: Korea University Industrial & Academic Collaboration Foundation
- Current Assignee Address: KR Seoul
- Agency: Chirstie, Parker & Hale, LLP
- Priority: KR10-2007-0133747 20071218; KR10-2008-0059380 20080624
- Main IPC: C12Q1/02
- IPC: C12Q1/02 ; G01N21/77 ; G01N21/76
Abstract:
Provided are two-photon fluorescent probes for imaging acidic vesicles in live cells and tissue. The probes are represented by The probes can selectively bind to vesicles in cytosol to emit two-photon excited fluorescence with high intensity. Therefore, the use of the probes enables effective imaging of acidic vesicles. Further provided is a method for imaging acidic vesicles in live cells and tissue using the probes.
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