Methods, apparatus, and products are disclosed for remotely booting computing nodes in a switching domain, the switching domain capable of connecting to other switching domains through a network switch, that include: receiving, in the switch, a wakeup request packet that requests activation of one or more computing nodes in the switching domain, the wakeup request packet having a process port value specifying physical ports on the switch to which the one or more computing nodes are physically connected; identifying, by the switch, a network address for each computing node in dependence upon the physical port on the switch to which each computing node to be activated is physically connected; generating, by the switch, a wakeup packet for each computing node in dependence upon the identified network address for that computing node; and transmitting, by the switch to each computing node to be activated, the wakeup packet for that computing node.