Invention Grant
- Patent Title: Process for the preparation of levetiracetam
- Patent Title (中): 左乙拉西坦的制备方法
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Application No.: US12561616Application Date: 2009-09-17
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Publication No.: US07939676B2Publication Date: 2011-05-10
- Inventor: Corrado Colli , Massimiliano Forcato , Livius Cotarca
- Applicant: Corrado Colli , Massimiliano Forcato , Livius Cotarca
- Applicant Address: IT Bresso (MI)
- Assignee: Zach System S.p.A.
- Current Assignee: Zach System S.p.A.
- Current Assignee Address: IT Bresso (MI)
- Agency: Lucas & Mercanti, LLP
- Main IPC: C07D207/06
- IPC: C07D207/06 ; C07D207/08

Abstract:
A process for the manufacturing of levetiracetam, wherein said process comprises the steps of: (1) reacting the (−)-(S)-alpha-ethyl-2-oxo-1-pyrrolidine acetic acid with a substoichiometric amount of an activating agent in an alcoholic solvent, and (2) subjecting the resulting reaction solution of step (1) to an ammonolysis process with gaseous ammonia.
Public/Granted literature
- US20110065932A1 Process for the preparation of Levetiracetam Public/Granted day:2011-03-17
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