Invention Grant
- Patent Title: Process for forming amorphous atorvastatin
- Patent Title (中): 形成无定形阿托伐他汀的方法
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Application No.: US11666707Application Date: 2005-10-12
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Publication No.: US07939675B2Publication Date: 2011-05-10
- Inventor: Antone John deBettencourt, III , Evgenyi Yur'evich Shalaev
- Applicant: Antone John deBettencourt, III , Evgenyi Yur'evich Shalaev
- Applicant Address: US NY New York
- Assignee: Pfizer, Inc.
- Current Assignee: Pfizer, Inc.
- Current Assignee Address: US NY New York
- Agent Jennifer A. Kispert; Francis J. Tinney
- International Application: PCT/IB2005/003173 WO 20051012
- International Announcement: WO2006/046109 WO 20060504
- Main IPC: C07D207/412
- IPC: C07D207/412
Abstract:
A process for forming amorphous atorvastatin comprising the steps of dissolving atorvastatin in a non-hydroxylic solvent and removing the solvent by freeze-drying, as well as processes of dissolving atorvastatin in a hydroxylic solvent with a solubilizing agent or an alkalizing agent or an antioxidant and removing the solvent by freeze-drying to afford amorphous atorvastatin.
Public/Granted literature
- US20080269314A1 Process for Forming Amorphous Atorvastatin Public/Granted day:2008-10-30
Information query
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