Invention Grant
US07939555B2 Method of preparing a pharmaceutical cream and minimizing imiquimod impurity formation
有权
制备药物霜剂并使咪喹莫特杂质形成最小化的方法
- Patent Title: Method of preparing a pharmaceutical cream and minimizing imiquimod impurity formation
- Patent Title (中): 制备药物霜剂并使咪喹莫特杂质形成最小化的方法
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Application No.: US12697439Application Date: 2010-02-01
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Publication No.: US07939555B2Publication Date: 2011-05-10
- Inventor: Alexis S. Statham , Robert J. Nelson
- Applicant: Alexis S. Statham , Robert J. Nelson
- Applicant Address: US MN St. Paul
- Assignee: 3M Innovative Properties Company
- Current Assignee: 3M Innovative Properties Company
- Current Assignee Address: US MN St. Paul
- Agency: Edwards Angell Palmer & Dodge LLP
- Agent Peter J. Manso
- Main IPC: A01N43/52
- IPC: A01N43/52 ; A01N43/42 ; A61K31/415 ; A61K31/44 ; C07D235/02

Abstract:
Pharmaceutical formulations and methods including an immune response modifier (IRM) compound and an oleic acid component are provided where stability is improved by using oleic acid have low polar impurities such as peroxides.
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