Invention Grant
US07884260B2 Cell-based screen for agents useful for reducing neuronal demyelination or promoting neuronal remyelination
失效
用于减少神经元脱髓鞘或促进神经元髓鞘再生的用于细胞的屏幕
- Patent Title: Cell-based screen for agents useful for reducing neuronal demyelination or promoting neuronal remyelination
- Patent Title (中): 用于减少神经元脱髓鞘或促进神经元髓鞘再生的用于细胞的屏幕
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Application No.: US11431601Application Date: 2006-05-09
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Publication No.: US07884260B2Publication Date: 2011-02-08
- Inventor: Brian Popko , Wensheng Lin
- Applicant: Brian Popko , Wensheng Lin
- Applicant Address: US IL Chicago
- Assignee: University of Chicago
- Current Assignee: University of Chicago
- Current Assignee Address: US IL Chicago
- Agency: Wilson Sonini Goodrich & Rosati
- Main IPC: G01N33/00
- IPC: G01N33/00 ; A01K67/00

Abstract:
This invention is in the field of neurology. Specifically, the invention relates to the discovery and characterization of molecular components that play a role in neuronal demyelination or remyelination. In addition, the invention relates to the generation of an animal model that exhibits hypomyelination. The compositions and methods embodied in the present invention are particularly useful for drug screening and/or treatment of demyelination disorders.
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