Invention Grant
- Patent Title: N-phenyloxamide derivatives
- Patent Title (中): N-苯基酰胺衍生物
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Application No.: US11870741Application Date: 2007-10-11
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Publication No.: US07884234B2Publication Date: 2011-02-08
- Inventor: Youichi Yamaguchi , Takeshi Yanase , Susumu Muto , Akiko Itai
- Applicant: Youichi Yamaguchi , Takeshi Yanase , Susumu Muto , Akiko Itai
- Applicant Address: JP Tokyo
- Assignee: Institute of Medicinal Molecular Design, inc.
- Current Assignee: Institute of Medicinal Molecular Design, inc.
- Current Assignee Address: JP Tokyo
- Agency: Greenblum & Bernstein, P.L.C.
- Priority: JP2006-278529 20061012
- Main IPC: C07C229/00
- IPC: C07C229/00

Abstract:
A compound represented by the following general formula (I) or a salt thereof, or a hydrate thereof or a solvate thereof having an inhibitory action against plasminogen activator inhibitor-1 (PAI-1): wherein R1 represents a C6-10 aryl group; or a C6-10 aryl group substituted with a group or groups selected from the group consisting of a halogen atom, cyano group, nitro group, a C1-6 alkyl group, a halogenated C1-6 alkyl group, a C1-6 alkoxy group, a halogenated C1-6 alkoxy group and a C1-6 alkylsulfanyl group, R2 represents a C6-10 aryl group; or a C6-10 aryl group substituted with a group or groups selected from the group consisting of a halogen atom, hydroxy group, a C1-6 alkyl group, a halogenated C1-6 alkyl group, a C1-6 alkoxy group, a halogenated C1-6 alkoxy group, a C1-6 alkylsulfanyl group and phenyl group, X represents a single bond or oxygen atom, Z represents a phenylene group or a substituted phenylene group, m represents 0 or 1.
Public/Granted literature
- US20090215899A9 N-Phenyloxamide derivatives Public/Granted day:2009-08-27
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