Invention Grant
US07884217B2 Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
有权
吡咯烷化合物和选择性抑制二肽基肽酶-IV的方法
- Patent Title: Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
- Patent Title (中): 吡咯烷化合物和选择性抑制二肽基肽酶-IV的方法
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Application No.: US11930337Application Date: 2007-10-31
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Publication No.: US07884217B2Publication Date: 2011-02-08
- Inventor: David Alan Campbell , David T. Winn , Juan Manuel Betancort
- Applicant: David Alan Campbell , David T. Winn , Juan Manuel Betancort
- Applicant Address: US CA San Diego
- Assignee: Phenomix Corporation
- Current Assignee: Phenomix Corporation
- Current Assignee Address: US CA San Diego
- Agency: Schwegman, Lundberg & Woessner, P.A.
- Main IPC: A61K31/69
- IPC: A61K31/69 ; C07F5/02
Abstract:
The present invention is directed to pyrrolidinylaminoacetyl pyrrolidine boronic acid compounds that display selective, potent dipeptidyl peptidase IV inhibitory activity. These compounds are useful for the treatment of disorders that can be regulated or normalized via inhibition of DPP-IV including those characterized by impaired glycemic control such as Diabetes Mellitus and related conditions. The compounds can be administered alone or with another medicament that displays pharmacological activity for treatment of these and other diseases.
Public/Granted literature
- US20080182995A1 PYRROLIDINE COMPOUNDS AND METHODS FOR SELECTIVE INHIBITION OF DIPEPTIDYL PEPTIDASE-IV Public/Granted day:2008-07-31
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