Invention Grant
US07884216B2 Fluorine-containing pyrazolecarbonitrile derivative and method for producing the same, and fluorine-containing pyrazolecarboxylic acid derivative obtained by using the fluorine-containing pyrazolecarbonitrile derivative and method for producing the same
有权
含氟吡唑腈衍生物及其制造方法以及使用含氟吡唑腈衍生物得到的含氟吡唑甲酸衍生物及其制造方法
- Patent Title: Fluorine-containing pyrazolecarbonitrile derivative and method for producing the same, and fluorine-containing pyrazolecarboxylic acid derivative obtained by using the fluorine-containing pyrazolecarbonitrile derivative and method for producing the same
- Patent Title (中): 含氟吡唑腈衍生物及其制造方法以及使用含氟吡唑腈衍生物得到的含氟吡唑甲酸衍生物及其制造方法
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Application No.: US12527739Application Date: 2008-02-13
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Publication No.: US07884216B2Publication Date: 2011-02-08
- Inventor: Hideki Umetani , Takeshi Kakimoto , Yoji Aoki
- Applicant: Hideki Umetani , Takeshi Kakimoto , Yoji Aoki
- Applicant Address: JP Minato-Ku, Tokyo
- Assignee: Mitsui Chemicals Agro, Inc.
- Current Assignee: Mitsui Chemicals Agro, Inc.
- Current Assignee Address: JP Minato-Ku, Tokyo
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: JP2007-039744 20070220
- International Application: PCT/JP2008/052357 WO 20080213
- International Announcement: WO2008/102678 WO 20080828
- Main IPC: C07D231/10
- IPC: C07D231/10 ; A61K31/415 ; A01N43/56

Abstract:
The present invention provides a fluorine-containing pyrazolecarbonitrile derivative and a method for producing the same, and a fluorine-containing pyrazolecarboxylic acid derivative obtained by using the fluorine-containing pyrazolecarbonitrile derivative and a method for producing the same.A fluorine-containing acyacrylonitrile derivative prepared from a fluoroacyl derivative and an aminoacrylonitrile derivative, is reacted with a hydrazine derivative to produce a fluorine-containing pyrazolecarbonitrile derivative represented by Formula (1). In Formula (1), Rf represents an alkyl group having 1 to 6 carbon atoms and substituted with at least one fluorine atom; R1 represents an alkyl group having 1 to 6 carbon atoms and R2 represents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or the like.The fluorine-containing pyrazolecarbonitrile derivative represented by Formula (1) is reacted with water to produce a fluorine-containing pyrazolecarboxylic acid derivative.
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