Invention Grant
US07884186B2 Isotopically labeled trapping agent and method for identifying reactive metabolites
有权
同位素标记的捕获剂和鉴定活性代谢物的方法
- Patent Title: Isotopically labeled trapping agent and method for identifying reactive metabolites
- Patent Title (中): 同位素标记的捕获剂和鉴定活性代谢物的方法
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Application No.: US11860056Application Date: 2007-09-24
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Publication No.: US07884186B2Publication Date: 2011-02-08
- Inventor: Norman D. Huebert , Zhengyin Yan
- Applicant: Norman D. Huebert , Zhengyin Yan
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agent Mary A. Appollina
- Main IPC: A61K38/06
- IPC: A61K38/06
Abstract:
The present invention is directed to an isotopically labeled trapping agent, methods for detecting reactive metabolites and methods of identifying drug candidates. More specifically, the isotopically labeled trapping agent and methods for detecting reactive metabolites may be used to detect both “hard” and “soft” reactive metabolites, thereby eliminating false positives.
Public/Granted literature
- US20080081349A1 ISOTOPICALLY LABELED TRAPPING AGENT AND METHOD FOR IDENTIFYING REACTIVE METABOLITES Public/Granted day:2008-04-03
Information query
IPC分类:
