Invention Grant
- Patent Title: Squaric acid derivatives as inhibitors of histone deacetylase
- Patent Title (中): 方酸衍生物作为组蛋白脱乙酰酶的抑制剂
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Application No.: US12090771Application Date: 2006-10-23
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Publication No.: US07884105B2Publication Date: 2011-02-08
- Inventor: Kristof Van Emelen
- Applicant: Kristof Van Emelen
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica, N.V.
- Current Assignee: Janssen Pharmaceutica, N.V.
- Current Assignee Address: BE Beerse
- Agency: Patton Boggs LLP
- Priority: EP05110080 20051027
- International Application: PCT/EP2006/067656 WO 20061023
- International Announcement: WO2007/048767 WO 20070503
- Main IPC: C07D239/42
- IPC: C07D239/42 ; C07D401/12 ; A61K31/505 ; A61K31/506
Abstract:
This invention comprises the novel compounds of formula (I) wherein R1, R2 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Public/Granted literature
- US20080255140A1 Squaric Acid Derivatives as Inhibitors of Histone Deacetylase Public/Granted day:2008-10-16
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